Jack Nicholson
Melvin Udall
Helen Hunt
Carol Connelly
Greg Kinnear
Simon Bishop
Cuba Gooding Jr.
Frank Sachs
Shirley Knight
Beverly Connelly
Jesse James
Spencer Connelly
Yeardley Smith
Jackie Simpson
Lupe Ontiveros
Nora Manning
Skeet Ulrich
Vincent Lopiano
Harold Ramis
Dr. Bettes
Lawrence Kasdan
Dr. Green
Bibi Osterwald
Neighbor Woman
Ross Bleckner
Carl
Bernadette Balagtas
Caterer
Alice Vaughn
Partygoer
Brian Doyle-Murray
Handyman
Kristi Zea
Mother at Table
Annie Maginnis Tippe
Daughter at Table
Patricia Childress
Cafe 24 Waitress
Rebekah Johnson
Cafe 24 Waitress
Missi Pyle
Cafe 24 Waitress
Leslie Stefanson
Cafe 24 Waitress
Tara Subkoff
Cafe 24 Waitress
Shane Black
Cafe 24 Manager
Peter Jacobson
Man at Table
Lisa Edelstein
Woman at Table
Randall Batinkoff
Carol's Date
Jamie Kennedy
Street Hustler
Justin Herwick
Street Hustler
Maya Rudolph
Policewoman
Dr. David A. Kipper
Hospital Doctor
Kathryn Morris
Psychiatric Patient
Wood Harris
Cafe 24 Busboy
Linda Gehringer
Publisher
Julie Benz
Receptionist
Antonia Jones
Nurse
Kaitlin Hopkins
Woman in Lobby
Jimmy Workman
Sean from the Bakery
Danielle Spencer
Veterinarian
Todd Solondz
Man on Bus
Tom McGowan
Maitre'd
Danielle Brisebois
Singer
Matt Malloy
Men's Store Salesman
Paul Greenberg
Bar Waiter
Amy Anzel
Ballet Dancer (uncredited)
Frank Slaten
Miffed Party Goer (uncredited)
Maurice LaMarche
Fred Bishop - Simon's Dad on Phone (voice) (uncredited)
Ava Lee Scott
New Yorker
