Joe Alaskey
Duck Dodgers / The Martian Commander (voice)
Bob Bergen
The Eager Young Space Cadet (voice)
Richard McGonagle
Dr. I.Q. Hi (voice)
Tia Carrere
The Martian Queen (voice)
Michael Dorn
Centurion Robot (voice)
Jeff Bennett
Ambassador Porkwellington / Narrator (voice)
John DiMaggio
Kilowog (voice)
John O'Hurley
Captain Star Johnson (voice)
Mako
Happy Cat (voice)
Dee Bradley Baker
Captain Richards / Giant Space Monkey (voice)
Henry Winkler
Dr. Maniac (voice)
Dave Mustaine
Himself (voice)
Grey DeLisle
Catapoid (voice)
Maurice LaMarche
K'chutha Sa'am (voice)
Jim Cummings
Tasmanian Devil / The Black Eel (voice)
Kevin Michael Richardson
Agent Roboto (voice)
Vanessa Marshall
Waitress / Woman #2 / Woman #3 (voice)
Billy West
The Mother Fudd / Zeke / Martian Commander (voice)
Tom Kane
The President of Outer Space (voice)
Chris Edgerly
Steve Boston (voice)
Michael Patrick McGill
Bigfoot / Yacht Owner (voice) (as Michael McGill)
Frank Welker
Ch'p (voice)
Michael Gough
Captain Glousterman / Professor / Reporter (voice)
Kevin Smith
Hal Jordan (voice)
Tress MacNeille
Sow (voice)
Loni Anderson
Herself (voice)
Jess Harnell
Puerco (voice)
Tom Jones
Tom Jones (voice)
Kelly Ripa
The New Cadet (voice)
June Foray
Lezah the Wicked (voice)
Macy Gray
Lady Chanticleer (voice)
Brian Wilson
Brian Wilson (voice)
Genndy Tartakovsky
Cyber Pirate of the Future (voice)
Tim Curry
Magnificent Rogue (voice)
Lewis Black
Manobrain (voice)
Quentin Tarantino
Master Moloch (voice)
Burt Reynolds
Royal Serpenti (voice)
Dom DeLuise
Roy Serpenti (voice)
Marc Singer
Kirk Manlord (voice)
Jennifer Hale
Pirate Lass / Becky - Wealthy Passenger (voice)
