Francesca Marie Smith
Helga Pataki (voice)
Jamil Walker Smith
Gerald Johanssen (voice)
Dan Castellaneta
Grandpa Phil (voice)
Justin Shenkarow
Harold Berman (voice)
Anndi McAfee
Phoebe Heyerdahl (voice)
Phillip Van Dyke
Arnold (voice)
Spencer Klein
Arnold (voice)
Olivia Hack
Rhonda Wellington Lloyd (voice)
Lane Toran
Arnold (voice)
Blake McIver Ewing
Eugene Horowitz (voice)
Craig Bartlett
Brainy (voice)
Tress MacNeille
Grandma Gertie (voice)
Kath Soucie
Miriam Pataki (voice)
Maurice LaMarche
Big Bob Pataki (voice)
Dom Irrera
Ernie Potts (voice)
Dan Butler
Mr. Simmons (voice)
David Wohl
Principal Wartz (voice)
Ben Diskin
Eugene Horowitz (voice)
Baoan Coleman
Mr. Hyunh (voice)
Adam Wylie
Curly Gammelthorpe (voice)
James Keane
Mr. Green (voice)
Lou Rawls
Harvey (voice)
Christopher Castile
Eugene Horowitz (voice)
Mary Scheer
Suzie Kokoshka (voice)
Nika Futterman
Olga Pataki (voice)
Marcus Toji
Park (voice)
Rick Fitts
Mr. Johanssen (voice)
Jordan Warkol
Chocolate Boy (voice)
John Mariano
Vic / Morrie (voice)
Shari Belafonte
Mrs. Johanssen (voice)
Michael Bacall
Torvald (voice)
Joey Paul Jensen
Seymour's Mother (voice)
Jarrett Lennon
Eugene Horowitz (voice)
Tony Jay
Rex Smythe-Higgins (voice)
Ashley Buccille
Lila Sawyer (voice)
Jim Belushi
Coach Wittenberg (voice)
Carlos Alazraqui
Nigel / Man (voice)
Lisa Fuson
Miss Slovak (voice)
Danielle Judovits
Patricia "Big Patty" Smith (voice)
Maria Bamford
Iggy's Mother (voice)
